See additional information. Along with these health benefits, the bark also has strong potential for weight loss, reducing inflammation, and improving sleep. Magnolia bark has been used in traditional Japanese and Chinese medicine for thousands of years. As part of his commitment to the advancement of integrative medicine, Dr. Eliaz partners with leading research institutes and has co-authored numerous peer-reviewed papers on innovative therapies for immune enhancement, heavy metal toxicity and cancer prevention and treatment. It comes from the Magnolia tree famous for its large, dramatic flowers. The goal is to create a multifaceted strategy that targets cancers multiple survival mechanisms with diverse, synergistic treatments. Magnolia bark continues to be used in dietary supplements today, marketed for potential benefits like reducing stress, decreasing inflammation, and as a natural sleep aid. Our website services, content, and products are for informational purposes only. The Tabebuia tree's bark is highly resistant to rotting, mold, and other common tree pathogens (bacteria, viruses, or other tiny organisms that may cause disease). WebMD does not provide medical advice, diagnosis or treatment. This suggests that it has potential as a therapeutic agent for neurodegenerative diseases like Alzheimers. The Extraordinary Importance of Sleep: The Detrimental Effects of Inadequate Sleep on Health and Public Safety Drive an Explosion of Sleep Research. Cortisol is the primary stress hormone in your body. and Yet again, clinical studies in humans need to be conducted. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Current microbiology, 77(9), 24132421. If cancer is smart, we have to be brilliant and with leading-edge integrative strategies, we can be. Researchers go on to mention that there were no toxic effects associated with honokiol. You can also try these other integrative recommendations for dealing with depression. In a clinical trial involving healthy, overweight, premenopausal women, Magnolia officinalis extract (MOE) demonstrated a weight loss effect on those that overate when they were stressed. Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABA(A) receptor in mice. More, Acid Reflux Diet: Best Foods, Foods to Avoid & Supplements that Help, Black Mold Symptoms + 12 Natural Remedies, Traditional Chinese Medicine Benefits, Herbs & Therapies. Thus, it cannot be said with certainty that the effects were due solely to the magnolia bark. Note that the numbers in parentheses (1, 2, etc.) Clinical studies will be required to determine whether it is safe or effective for any purpose. A., & Pugh, M. (2013). 3 Supplements To Consider. Save my name, email, and website in this browser for the next time I comment. Another study in 180 menopausal women determined that a supplement containing magnolia bark, soy isoflavones, and lactobacilli more effectively reduced the severity and frequency of hot flashes than a supplement containing the soy isoflavones alone (33). It supported stagnation, inflammation, anxiety, and bloating. One fascinating new study demonstrated that after 60 days of daily meditation practice, galectin-3 levels among heart disease patients were significantly reduced, compared to their original baseline. This article reviews galangal root's benefits and safety, as well as how it, Elecampane root is a folk medicine that may have several health benefits. https://doi.org/10.1111/j.1476-5381.2012.02010.x, Sarrica, A., Kirika, N., Romeo, M., Salmona, M., & Diomede, L. (2018). No adverse effects related to magnolia bark or the compounds it contains have been observed. It can even change the way your body manages stress, making it much harder to break the stress cycle. Related: Stress Hormones: How Diet Affects Hormonal Balance. But as the saying goes, no one wins in war. The shift from survival to wellness and harmony serves as the foundation of a truly holistic model of medicine, which we apply extensively in our clinic, Amitabha Medical Clinic in Santa Rosa, California. The supplement has been used in traditional Chinese medicine for thousands of years, and current research has confirmed that magnolia bark has many potential benefits for humans. Magnolia bark extract has been tested in studies as an ingredient in chewing gum. Other common names include Cucumber Tree, Magnoliae cortex, Swamp Sassafras, Houpo, and Honoki. This researched form of MCP has a very specific molecular weight and structure which allows it to enter the circulation from the digestive tract, and bind to the carbohydrate receptors on galectin-3 molecules, safely disarming them. Magnolia bark has been used for centuries to treat digestive problems, including nausea, abdominal pain and bloating, diarrhea, and loss of appetite. Grandchildren are some of lifes greatest treasures. A second study in mice observed similar outcomes after administering honokiol, which also decreased the amount of time it took the mice to fall asleep and transition into non-REM sleep (28). The magnolia is a deciduous tree that has multiple species that are native to eastern Asia, as well as the Americas. Magnolia Bark Extract Magnolia officinalis is a traditional chinese medicine known for its neuroprotective and relaxing properties, being used to treat depression and anxiety as well as acting as a slight sedative. Stress isnt just a feeling its a whole system of physical reactions that are supposed to keep you safe from imminent danger. How Was Magnolia Used Historically in Traditional Medicine? Safety Class: 2b (Not to be used during pregnancy). Before supplementing with magnolia bark, check with your medical provider to discuss proper dosage levels and ensure theres no risk of potential interactions with any medications youre taking. summary The bark, leaves, and. The bark is harvested from April to June where it is then dried in shade. Today, magnolia bark is still used in these two traditional medicinal formulas: In the western world, the magnolia tree was first seen in North Carolina during the 16th century. https://doi.org/10.3748/wjg.v11.i28.4414, Zhang, Y. J., Li, S., Gan, R. Y., Zhou, T., Xu, D. P., & Li, H. B. Thats when survival mode transforms into a threat on its own. So how exactly do we solve this paradox? These various health benefits are attributed to magnolol and honokiol, two phenolic compounds present in magnolia bark. The bark is slightly decocted, steamed, and then rolled and dried once the color is purple-brown. Dr. Jeffrey Barke, MD, is a Family Medicine specialist practicing in Newport Beach, CA with 33 years of experience. A similar study in more than 600 menopausal women found that consuming a magnolia bark supplement daily for 12 weeks relieved symptoms of insomnia, irritability, and anxiety (32). Although commonly found in traditional Chinese and Japanese medicine, magnolia bark was also traditionally used in Native American medicine. As an integrative MD and researcher, licensed acupuncturist and life-long practitioner of Buddhist meditation, I've developed a unique perspective and methodology around mind-body medicine, and specifically, our innate abilities to heal ourselves and others. https://doi.org/10.1093/jpp/rgab067, Chen, C. R., Zhou, X. In a mouse study, honokiol proved to elicit the anxiolytic effect in Hange-koboku-to and Saiboku-to, two medicines used in traditional Chinese medicine and Kampo (traditional Japanese medicine). For mild to moderate depression, I recommend exercise 30 minutes a day. Beach Animal Rehabilitation Center (BARC) is a one of a kind veterinary clinic, serving Los Angeles and Orange Counties, specializing in rehabilitation for dogs and cats. Cultivation and therapeutic use also date back to the Native Americans and ancient Aztecs. Jf Pryor, the founder of The REAL Bark, claimed that Thor's eyes begged, "Let me live. 2023 Dr. Axe. Their sole purpose is to help you survive by stimulating fight or flight action. The supplement can not only help improve sleep, stress, anxiety, and symptoms of menopause but also may have anticancer and antioxidant properties. Research shows that magnolia bark benefits sleep quality. There are many potential health benefits of magnolia bark offered by two key micronutrients magnolol and honokiol present in it. Magnolol inhibited cancer growth and reduced tumor size in vitro. Magnolia bark is considered a safe supplement for human consumption. This study also supports previous research showing that regular meditation reduces other pro-cancer proteins like TNF-alpha and CRP these inflammatory markers are triggered by the master regulator, galectin-3. For digestive problems, magnolia bark. Note that the numbers in parentheses (1, 2, etc.) 4 But in this study, pine pollen was combined with metformin, a drug that can cause those side effects. Because, obviously, we want to survive any life-threatening condition. The calming effects are unlike anything we have come across and produce a very comprehensive effect. The Journal of pharmacy and pharmacology, 73(9), 11611168. Magnolia bark extract is readily available in pill form. Some researchers believe that these effects are due to honokiol, a natural compound in the bark. It produces mature red, conelike fruit from September through October when it opens up to display its seeds. The houpo magnolia tree is native to China, where it has been used for thousands of years as a supplement in traditional Chinese medicine. Lastly, a study in rodents noted that a mixture of honokiol and magnolol caused antidepressant-like effects, including improvements in serotonin levels in the brain and reductions in corticosterone levels in the blood (26). 2011-2022 Examine.com Inc. Privacy Policy | Terms of Service. It was also valued in TCM for its ability to reduce inflammation, anxiety, and bloating.. White oak bark may benefit both human hair and skin. He is founder and medical director ofAmitabha Medical Clinic and Healing Center in Santa Rosa, CA, where he and his team of practitioners pioneer individualized treatments for cancer and chronic illness. Its primary compound, honokiol, has been shown to reduce the time it takes to fall asleep by binding to GABA receptors in the brain, which help prompt sleep. All these barks are then stacked up in a wet area. https://doi.org/10.3858/emm.2008.40.6.617, Huang, K. J., Kuo, C. H., Chen, S. H., Lin, C. Y., & Lee, Y. R. (2018). Many of its traditional uses have been scientifically tested (via animal and in vitro trials) and show promising results. Below are the top researched-backed magnolia bark benefits for health. Healthline Media does not provide medical advice, diagnosis, or treatment. Were making great strides in the treatment of cancer 16.9 million survivors in the United States can testify to that. It can grow at an additional height of 24 inches per year. Although there isnt much historical information on the magnolia tree and magnolia bark in Asia, there were sightings of the tree in North Carolina as early as the 16th century. A 24-week study in 89 menopausal women experiencing symptoms of sleep and mood alterations were given a supplement containing 60 mg of magnolia bark extract and 50 mg of magnesium daily. Along with increasing your overall resilience, MCP blocks galectin-3, the alarm protein that triggers inflammation and causes many of the harmful effects associated with chronic stress. The Journal of pharmacy and pharmacology, 51(1), 97103. Are There Any Precautions to Consider While Taking Magnolia? One particular extract that exhibits remarkable ability against cancer is pure honokiol, a highly active molecule derived from Magnolia officinalis bark. Additionally, the magnolol appeared to increase the number of times the mice woke up during sleep but decrease the length of time they were awake. He needed to be stabilized, and then an impossible rehabilitation awaited. (2020). In a 2022 study, a supplement containing magnolia bark and phellodendron bark (Phellodendron amurense) was used to reduce stress and cortisol levels in 56 moderately-stressed participants. While the stem barks are decocted to a slight extent in boiling water, the branch and root barks are dried in the shade. It belongs to the Magnoliaceae family and is a deciduous tree that can grow 16 ft to upwards of 80 ft depending on the species. It takes an enormous toll on your immune system, leaving you more vulnerable to any infection thats going around. Magnesium supplements can also interact with other drugs and change how they work in your body. Is It (Finally) Time to Stop Calling COVID a Pandemic? 2005 - 2023 WebMD LLC, an Internet Brands company. Its important to note that the exact mechanisms through which the isolated compounds contribute to these effects are still being investigated. This article lists 13 foods that have powerful anti-inflammatory effects to help lower chronic inflammation. Given that cancer is a disease characterized by abnormal cell division and growth, the ability to regulate cellular pathways is beneficial (16). Those reactions protect you when youre facing immediate, temporary threats like avoiding a car crash. Traditional Chinese Medicine (TCM) is an ancient form of healthcare that dates 7 Natural Ways to Relieve Stress & Calm Down Your Anxiety, Stress Hormones: How Diet Affects Hormonal Balance, clinically researched modified citrus pectin (MCP), Frankincense Essential Oil Uses and Benefits for Healing, Oregano Oil Benefits for Infections, Fungus & Even the Common Cold, L-Glutamine Benefits Leaky Gut & Metabolism, Secret Detox Drink Recipe (A Natural Detox Drink Recipe), Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More, Symptoms of Candida Overgrowth & How to Get Rid of It, Investing in Your Grandkids Future? ( a ) receptor in mice website in this browser for the next time I.... Wins in war we want to survive any life-threatening condition note that the numbers in parentheses 1. Height of 24 inches per year molecule derived from magnolia officinalis bark their sole purpose is to create multifaceted. 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